Firecrawl Alexandria

PubMed and PMC

Biomedical literature from PubMed and PubMed Central (NIH National Library of Medicine): search with PubMed query syntax, document summaries, full article records with abstracts and MeSH indexing, PMID/PMCID/DOI resolution, similar and citing articles, and open-access full text. Uses NCBI's anonymous programmatic services (E-utilities, PMC ID Converter, BioC) only; the PubMed and PMC websites themselves sit behind a proof-of-work challenge and are not scraped.

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14 Firecrawl tools use PubMed and PMC

Try PubMed and PMC now.

Choose an example or ask your own question.

PubMed and PMC
TRY ASKING
1Request
stringRequired

PubMed query; free text or field-tagged syntax exactly as accepted by the PubMed search box.

string

Entrez database: `pubmed` (citations and abstracts) or `pmc` (PubMed Central full-text articles).

boolean

When false, skip the esummary call and return ids only (one upstream request instead of two).

number

Results per page (esearch retmax).

5 credits
Codefollows the fields above
const result = await firecrawl.scrape({
  alexandria: {
    provider: "pubmed-ncbi-nlm-nih-gov",
    capability: "publications/search",
    options: {
      query: "crispr gene editing",
    },
  },
});
2Response example

This is a sample shape. Press Run to see live data from PubMed and PMC.

{
  "db": "pubmed",
  "ids": [
    "42779897",
    "42779610",
    "42778074",
    "42777870",
    "42775150",
    "42775062",
    "42772798",
    "42772585",
    "42772422",
    "42771583",
    "42771352",
    "42771324",
    "42771323",
    "42771322",
    "42771321",
    "42771320",
    "42771319",
    "42771318",
    "42771317",
    "42771316"
  ],
  "limit": 20,
  "messages": [],
  "next_offset": 20,
  "observed_at_ms": 1790282876532,
  "offset": 0,
  "query": "crispr gene editing",
  "query_translation": "(\"clustered regularly interspaced short palindromic repeats\"[MeSH Terms] OR (\"clustered\"[All Fields] AND \"regularly\"[All Fields] AND \"interspaced\"[All Fields] AND \"short\"[All Fields] AND \"palindromic\"[All Fields] AND \"repeats\"[All Fields]) OR \"clustered regularly interspaced short palindromic repeats\"[All Fields] OR \"crispr\"[All Fields] OR \"crisprs\"[All Fields]) AND (\"gene editing\"[MeSH Terms] OR (\"gene\"[All Fields] AND \"editing\"[All Fields]) OR \"gene editing\"[All Fields])",
  "results": [
    {
      "authors": [
        "Nejat N",
        "van Warmerdam T",
        "Rasgon JL"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.64898/2026.09.14.751565",
      "epub_date": "2026 Sep 17",
      "id": "42779897",
      "issue": null,
      "journal": "bioRxiv",
      "journal_full": "bioRxiv : the preprint server for biology",
      "languages": [
        "eng"
      ],
      "last_author": "Rasgon JL",
      "pages": null,
      "pmcid": "PMC13596310",
      "pmid": "42779897",
      "pub_date": "2026 Sep 17",
      "publication_types": [
        "Journal Article",
        "Preprint"
      ],
      "record_status": "PubMed",
      "title": "Infectious transgenesis in arthropods.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42779897/",
      "volume": null
    },
    {
      "authors": [
        "Hamilton MC",
        "Riley JW",
        "Nelson AC",
        "Li B",
        "Dornbaum SF",
        "Safi A",
        "Cui X",
        "Jones IR",
        "Coley AA",
        "Hagy KT",
        "Rai R",
        "Barrera A",
        "Allen AS",
        "Shen Y",
        "Sherwood RI",
        "Love MI",
        "Sullivan PF",
        "Gersbach CA",
        "Crawford GE"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.64898/2026.09.03.749158",
      "epub_date": "2026 Sep 17",
      "id": "42779610",
      "issue": null,
      "journal": "bioRxiv",
      "journal_full": "bioRxiv : the preprint server for biology",
      "languages": [
        "eng"
      ],
      "last_author": "Crawford GE",
      "pages": null,
      "pmcid": "PMC13596172",
      "pmid": "42779610",
      "pub_date": "2026 Sep 17",
      "publication_types": [
        "Journal Article",
        "Preprint"
      ],
      "record_status": "PubMed",
      "title": "Interrogation of noncoding schizophrenia risk variants using CRISPR-based functional genomics.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42779610/",
      "volume": null
    },
    {
      "authors": [
        "Raihan M",
        "Younas I",
        "Su S",
        "Xu L"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1016/j.plantsci.2026.113465",
      "epub_date": "2026 Sep 23",
      "id": "42778074",
      "issue": null,
      "journal": "Plant Sci",
      "journal_full": "Plant science : an international journal of experimental plant biology",
      "languages": [
        "eng"
      ],
      "last_author": "Xu L",
      "pages": "113465",
      "pmcid": null,
      "pmid": "42778074",
      "pub_date": "2026 Sep 23",
      "publication_types": [
        "Journal Article",
        "Review"
      ],
      "record_status": "PubMed - as supplied by publisher",
      "title": "Molecular Mechanisms of WRKY Transcription Factors Integrating Environmental Signals to Regulate Flowering Time in Brassica Crops.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42778074/",
      "volume": null
    },
    {
      "authors": [
        "Wang F",
        "Liu X",
        "Gu W",
        "Xie X",
        "Wu S",
        "Gao S",
        "Srimongkol P",
        "Srinuanpan S",
        "Karnchanatat A",
        "Wang G"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1016/j.biortech.2026.135918",
      "epub_date": "2026 Sep 23",
      "id": "42777870",
      "issue": null,
      "journal": "Bioresour Technol",
      "journal_full": "Bioresource technology",
      "languages": [
        "eng"
      ],
      "last_author": "Wang G",
      "pages": "135918",
      "pmcid": null,
      "pmid": "42777870",
      "pub_date": "2026 Sep 23",
      "publication_types": [
        "Journal Article",
        "Review"
      ],
      "record_status": "PubMed - as supplied by publisher",
      "title": "Microalgal proteins as sustainable alternatives: CRISPR opportunities and challenges.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42777870/",
      "volume": null
    },
    {
      "authors": [
        "Liyanage R",
        "Jin L",
        "Chen SJ"
      ],
      "cited_by_count_pmc": 85,
      "db": "pubmed",
      "doi": "10.1088/3049-477X/aea331",
      "epub_date": "2026 Sep 17",
      "id": "42775150",
      "issue": "2",
      "journal": "Mach Learn Health",
      "journal_full": "Machine learning. Health",
      "languages": [
        "eng"
      ],
      "last_author": "Chen SJ",
      "pages": "021001",
      "pmcid": "PMC13595359",
      "pmid": "42775150",
      "pub_date": "2026 Dec 31",
      "publication_types": [
        "Journal Article",
        "Review"
      ],
      "record_status": "PubMed",
      "title": "Machine-learning in optimization of CRISPR technology.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42775150/",
      "volume": "2"
    },
    {
      "authors": [
        "Yamashita T",
        "Naito Y",
        "Yamamoto T",
        "Yoshida T",
        "Uchida Y",
        "Uchida E",
        "Inoue T"
      ],
      "cited_by_count_pmc": 28,
      "db": "pubmed",
      "doi": "10.1016/j.omta.2026.201837",
      "epub_date": "2026 Sep 1",
      "id": "42775062",
      "issue": "4",
      "journal": "Mol Ther Adv",
      "journal_full": "Molecular therapy. Advances",
      "languages": [
        "eng"
      ],
      "last_author": "Inoue T",
      "pages": "201837",
      "pmcid": "PMC13595080",
      "pmid": "42775062",
      "pub_date": "2026 Dec 10",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed",
      "title": "Digenome-Detect: Accurate, statistics-based analysis software for identifying off-target cleavage sites in genome editing.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42775062/",
      "volume": "34"
    },
    {
      "authors": [
        "Huang Y",
        "Liu X",
        "Fan G",
        "Gong G",
        "Lee SM"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1111/bph.70662",
      "epub_date": "2026 Sep 22",
      "id": "42772798",
      "issue": null,
      "journal": "Br J Pharmacol",
      "journal_full": "British journal of pharmacology",
      "languages": [
        "eng"
      ],
      "last_author": "Lee SM",
      "pages": null,
      "pmcid": null,
      "pmid": "42772798",
      "pub_date": "2026 Sep 22",
      "publication_types": [
        "Journal Article",
        "Review"
      ],
      "record_status": "PubMed - as supplied by publisher",
      "title": "Zebrafish in the era of single-cell and spatial transcriptomics: a new paradigm for central nervous system drug discovery from natural products.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42772798/",
      "volume": null
    },
    {
      "authors": [
        "Javadi K",
        "Zebardast A"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1016/j.gene.2026.150416",
      "epub_date": "2026 Sep 22",
      "id": "42772585",
      "issue": null,
      "journal": "Gene",
      "journal_full": "Gene",
      "languages": [
        "eng"
      ],
      "last_author": "Zebardast A",
      "pages": "150416",
      "pmcid": null,
      "pmid": "42772585",
      "pub_date": "2026 Sep 22",
      "publication_types": [
        "Journal Article",
        "Review"
      ],
      "record_status": "PubMed - as supplied by publisher",
      "title": "Targeting host factors in antiviral therapy: new frontiers in combating viral infections.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42772585/",
      "volume": null
    },
    {
      "authors": [
        "Elkhadragy L",
        "David OG",
        "Castillo CC",
        "Redlon LN",
        "Jordan LR",
        "Khan N",
        "Liu H",
        "Rosa Lopes IA",
        "Zhou Y",
        "Kanzaki H",
        "Hoshida Y",
        "Samuelson JP",
        "Lujambio A",
        "Schook LB",
        "Guzman G",
        "Schachtschneider KM",
        "Gaba RC"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1016/j.jhepr.2026.102042",
      "epub_date": "2026 Sep 22",
      "id": "42772422",
      "issue": null,
      "journal": "JHEP Rep",
      "journal_full": "JHEP reports : innovation in hepatology",
      "languages": [
        "eng"
      ],
      "last_author": "Gaba RC",
      "pages": "102042",
      "pmcid": null,
      "pmid": "42772422",
      "pub_date": "2026 Sep 22",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - as supplied by publisher",
      "title": "Modeling Liver Cancer Molecular and Histological Features by CRISPR Editing of Porcine Hepatocytes.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42772422/",
      "volume": null
    },
    {
      "authors": [
        "Hall ML",
        "Quintal A",
        "Acharya SN",
        "Worme S",
        "Nguyen TT",
        "Schonrock Z",
        "Tsuchiya M",
        "Carlson HL",
        "Pacentine IV",
        "Shrestha SB",
        "Macaraeg J",
        "Armstrong R",
        "Szczepanski N",
        "Adler J",
        "McGann J",
        "Evans-Dutson S",
        "Lusardi TA",
        "O'Connell BL",
        "Adey AC",
        "Yardımcı GG",
        "Maxson JE",
        "Braun TP"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1182/blood.2026034001",
      "epub_date": "2026 Sep 22",
      "id": "42771583",
      "issue": null,
      "journal": "Blood",
      "journal_full": "Blood",
      "languages": [
        "eng"
      ],
      "last_author": "Braun TP",
      "pages": null,
      "pmcid": null,
      "pmid": "42771583",
      "pub_date": "2026 Sep 22",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - as supplied by publisher",
      "title": "Mutant ASXL1 Cooperates with MECOM and BRD4 to Drive Transcriptional Dysregulation in Human Hematopoiesis.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771583/",
      "volume": null
    },
    {
      "authors": [
        "Saltzman RG",
        "Asensi KD",
        "Chakraborty A",
        "Kulandavelu S",
        "Hare JM"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1080/14779072.2026.2735936",
      "epub_date": "2026 Sep 22",
      "id": "42771352",
      "issue": null,
      "journal": "Expert Rev Cardiovasc Ther",
      "journal_full": "Expert review of cardiovascular therapy",
      "languages": [
        "eng"
      ],
      "last_author": "Hare JM",
      "pages": null,
      "pmcid": null,
      "pmid": "42771352",
      "pub_date": "2026 Sep 22",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - as supplied by publisher",
      "title": "Beating the heart failure epidemic: can emerging cell therapies deliver what conventional approaches cannot?",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771352/",
      "volume": null
    },
    {
      "authors": [
        "Vaskovicova M",
        "Dolejs V",
        "Dostalova P",
        "Michalikova CS",
        "Prochazka J",
        "Sedlacek R"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_21",
      "epub_date": null,
      "id": "42771324",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Sedlacek R",
      "pages": "411-421",
      "pmcid": null,
      "pmid": "42771324",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Delivery of Targeting Constructs into Zygotes Using Electroporation.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771324/",
      "volume": "3075"
    },
    {
      "authors": [
        "Ortiz-Bueno M",
        "Millán-López A",
        "Labun K",
        "Benabdellah K"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_20",
      "epub_date": null,
      "id": "42771323",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Benabdellah K",
      "pages": "389-409",
      "pmcid": null,
      "pmid": "42771323",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Nucleofection-Based CRISPR/Cas Delivery in Human T Cells for Immunotherapy Applications.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771323/",
      "volume": "3075"
    },
    {
      "authors": [
        "Peña-Gutierrez I",
        "Mazzeo D",
        "Bassons-Bascuñana A",
        "Haider S",
        "Garcia-Garcia L",
        "Olalla-Sastre B",
        "Río P",
        "López-Manzaneda S",
        "Mataix M"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_19",
      "epub_date": null,
      "id": "42771322",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Mataix M",
      "pages": "367-388",
      "pmcid": null,
      "pmid": "42771322",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "An Electroporation-Based Protocol for Ex Vivo Base Editing: From Design to Quantitative Assessment.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771322/",
      "volume": "3075"
    },
    {
      "authors": [
        "Papaioannou NY",
        "Papasavva PL",
        "Patsali P",
        "Lederer CW"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_18",
      "epub_date": null,
      "id": "42771321",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Lederer CW",
      "pages": "341-366",
      "pmcid": null,
      "pmid": "42771321",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Electroporation for High-Efficiency Delivery of CRISPR to Hematopoietic Cells.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771321/",
      "volume": "3075"
    },
    {
      "authors": [
        "Skrbinek M",
        "Bohinc J"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_17",
      "epub_date": null,
      "id": "42771320",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Bohinc J",
      "pages": "327-339",
      "pmcid": null,
      "pmid": "42771320",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Production and Purification of Cas9 Protein for Ribonucleoprotein Complex Formation.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771320/",
      "volume": "3075"
    },
    {
      "authors": [
        "Carusillo A",
        "Naseem A",
        "Cavazza A"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_16",
      "epub_date": null,
      "id": "42771319",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Cavazza A",
      "pages": "311-324",
      "pmcid": null,
      "pmid": "42771319",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Virus-Like Particles as a Nonviral CRISPR/Cas Editing Delivery Tool.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771319/",
      "volume": "3075"
    },
    {
      "authors": [
        "Martí-Melero L",
        "Martín SP",
        "Gómez SB",
        "Guerra-Rebollo M"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_15",
      "epub_date": null,
      "id": "42771318",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Guerra-Rebollo M",
      "pages": "299-309",
      "pmcid": null,
      "pmid": "42771318",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Oligo-Modified Poly(β-Amino Ester)-Mediated mRNA Delivery: A Protocol for Gene Editing Applications.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771318/",
      "volume": "3075"
    },
    {
      "authors": [
        "Paul A",
        "Lee HY",
        "Tuma J"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_14",
      "epub_date": null,
      "id": "42771317",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Tuma J",
      "pages": "275-297",
      "pmcid": null,
      "pmid": "42771317",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Cell-Penetrating Peptide Delivery for CRISPR Applications.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771317/",
      "volume": "3075"
    },
    {
      "authors": [
        "Vasti C",
        "Valenti LE",
        "Giacomelli CE"
      ],
      "cited_by_count_pmc": null,
      "db": "pubmed",
      "doi": "10.1007/978-1-0716-5547-4_13",
      "epub_date": null,
      "id": "42771316",
      "issue": null,
      "journal": "Methods Mol Biol",
      "journal_full": "Methods in molecular biology (Clifton, N.J.)",
      "languages": [
        "eng"
      ],
      "last_author": "Giacomelli CE",
      "pages": "257-273",
      "pmcid": null,
      "pmid": "42771316",
      "pub_date": "2027",
      "publication_types": [
        "Journal Article"
      ],
      "record_status": "PubMed - indexed for MEDLINE",
      "title": "Quantitative Analysis of CRISPR Encoding Plasmid DNA-Nanocarrier Interactions by Gel Electrophoresis and Densitometry.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42771316/",
      "volume": "3075"
    }
  ],
  "source_url": "https://pubmed.ncbi.nlm.nih.gov/?term=crispr+gene+editing",
  "total_count": 25455
}

Firecrawl tools

14

Ready-made Firecrawl tools that call PubMed and PMC.

Quality, speed and cost, last 24 hours, across every agent call to PubMed and PMC through Alexandria.

Quality
99%
Calls answered without a tool error
Speed
1.4 s
95% of successful calls finish faster
Cost
5 credits
Firecrawl credits per call
Calls
2.8K
Last 24 hours, every Alexandria user
Quality and speed of each tool, last 24 hours
ToolQualitySpeedCalls
Article98.9%968 ms1.5K
Search99.3%2.2 s1.1K
Full text98.4%1.2 s126
Resolve ids90.5%4.6 s21
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